Reproduction Abstracts

ADGRD1 is a member of the adhesion G protein-coupled receptors (aGPCRs), a family of membrane proteins that are categorised by the presence of a GAIN (GPCR autoproteolysis-inducing) domain between a large N-terminal extracellular region that is thought to bind signal-initiating ligands, and the signal-transducing G-protein-coupled seven transmembrane helices. The role and function of many aGPRCs is unclear and most of them are ‘orphan’ receptors, having no identified...